score:5
The Emperor Charles V lived out his entire life on the European continent, with a few short visits to the north African coast. He definitely never visited the colonies in the Americas. Here's what I was able to find:
Easternmost Location: Vienna, in 1532, to fight off the armies of the Ottoman Empire.
Westernmost Location: Seville, in 1526, for his marriage to Isabella of Portugal. A close runner up is the Monastery of Yuste, in western Spain, which he retired to in 1557 until his death in 1558. He may have visited Portugal or Galicia further west, but I was unable to find any record of it.
References: The Wikipedia page for Charles V, the Encyclopedia Britannica page for Charles V, and The Autobiography of the Emperor Charles V
Upvote:3
Westernmost Location: Charles V was in Galicia, in A Coruña and Santiago de Compostela (42°52′N, 08°32′W) in 1520, where he called for the Cortes (Parliament) of Castille:
Ref.: