score:3
I have heard both sides of the situation: some have been stopped because they didn't put the liquid in a clear bag and some kept the liquid in the box without any issues.
The TSA says:
Placing these items in the small bag and separating from your carry-on baggage facilitates the screening process.
Since you have 25 COVID self-tests, the liquid has a high possibility of being detected when screening. To avoid any hold-ups, I recommend putting them in a clear bag to avoid any issues.