When did people first started to consider lead poisoning as a possible problem?

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According History of Lead Poisoning Around the World by Dr. Herbert L. Needleman, lead poisoning was first knowingly observed and recorded in a means which we can recover as early as 2000 BCE. Childhood lead poisoning was first discovered in 1892. It was banned by an international agreement in 1925, but the United States waited until 1970 to ban it.

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