Upvote:1
You cannot correct an already submitted DS-160 unless it’s denied for incorrect/incomplete answers and reopened by the consulate.
However, assuming it’s before your interview, you can generally submit a new DS-160 including the corrected information, and bring that confirmation to the interview appointment.
If you’ve already completed an interview/been issued a visa then it look likely depend on the specifics of the mistake. I.e. is it something that came up properly in the interview, and the DS-160 just had a simple typo, in which case I can’t imagine it matters at this point. Or is it something that looks like you hid something in which case it’s likely more problematic.