score:2
Yes you can.
Although the right answer is very dependent on your personal interests, here are a few pointers to get you started:
Do a 'free' walking tour. They work for tips, so it's not really free, but it's an easy and friendly way to get to know a bit of the city.
Spend time at Ibirapuera Park. There are several decent museums in the park, and it's a great place to relax and watch the world go by.
Spend an afternoon or evening exploring Vila Madelana, a lovely suburb full of restaurants and bars.