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Check out this article: Meditation as a Voluntary Hypometabolic State of Biological Estivation by John Ding-E Young and Eugene Taylor.
It's a really interesting, brief read. Basically, it is a review of several studies on the physiology of meditators. It provides evidence for the case that aspects of meditation may be similar to hibernation, or "hypometabolism". For example, like some bear species are able to not eat or drink for months on end (as far as I know) and come out fine, maybe meditators are able to lower their metabolism and thus meditate indefinitely without physiological upset. Some really cool examples of people meditating underground for days, or in airtight boxes for multiple hours with no ill effects.
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This is a Youtube video about long term meditation: The Boy With Divine Powers - Buddha Boy
A meditating teenage boy in south-central Nepal who went without food or water for 10 months has changed the way we look at modern science and medicine forever. In 2006, Discovery Channel film crew traveled to Nepal to establish if it was possible for a human to abstain from all sustenance, water included, by filming "Buddha Boy" continuously for four days and nights.