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These can arise if you do not develop the right type of concentration and awareness
If you abandon the above two meditation will reduce stress.
Kindness meditation also can help. 1st you should create peace and serenity in your mind and then wish you share this with other. If this is not there in your mind and / or you are not sincere, this will be just repeating words. So 1st examine your self to see if you have happiness within you then start kindness meditation.
Being week in morality also causes agitations and leads to manifestation of the hindrances. So you base of morality should be strong.
When past fabrications come up it gives different sensations. In this case most likely unpleasant or not being a sensation you crave for, which is causing the problem. What ever sensation or experience you get be equanimous. Then you will not get stressed.
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It's possible you're going through the Knowledge of Dispassion/Disgust stage described by Buddhaghosa in the Visuddhimagga, Mahasi Sayadaw, and modern authors like Daniel Ingram. I've gone through it too, and so have many others.
Generally, the clearest indication of this is whether or not you've crossed the Knowledge of Arising & Passing Away, as once you have, you tend to be stuck at stage 6 of the Visuddhimagga's Stages of Purification. However, some people (such as myself) wind up in stage 6 for the first time without any recollection of having done so.
Another indication is if you find yourself experiencing periods of strong equanimity interspersing periods of intensely negative feelings like disgust, fear or misery. Generally, these other feelings would be noticeable, but not necessarily for everyone - I've never had any strong feelings of fear in my practice, for example.
If the irritation is completely isolated though and remains that way, it's probably got some other cause such as heightened sensitivity.