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Some answers in the comment section: problems may arise from the presence of boats, water pollution, the ongoing political turbulence in Myanmar, giant stingrays (600kg) and crocodiles.
- Probably depends where, but I would think in many areas boats (potentially quite large) can be quite a danger. The quality of the water may also be less than ideal, if you're thinking about doing that for recreational purposes. – jcaron Apr 26 at 14:47
- If you are planning to do this at the golden triangle: you need to be a good swimmer: the river is quite wide there. There is also a risk of drifting into Myanmar which is definitely not a great spot to be at the moment. I'm also fairly sure it's forbidden to just jump in the water from any bank of the river by local immigration, but I have no data to back that up, – Hilmar Apr 26 at 15:11
- WWF says there are giant stingrays (600kg) and crocodiles, but they're endangered so probably not very likely to be encountered. – Nate Eldredge Apr 27 at 3:27