Does giving blood affect plane travel?

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I can only give my personal experience and non-medical biology teacher's opinion: I have flown within a few days of blood donations several times, both whole blood and platelet. There were no symptoms. A week later, your red cell count might be measurably lower than, say, 60 days later, but unless you plan to run long distances on the plane or something you probably wouldn't notice anything. Flying is just like going to moderate altitude, in terms of your physiology--unless going to Denver would be a problem you will be fine.

CarlF 238

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Source: stackoverflow.com

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