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From AA's site:
Changing flight awards Contact American Airlines Reservations for assistance with changing a flight award ticket.
Changes to the origin or destination or airline
For MileSAAver awards, origin or destination changes to the itinerary will incur a change fee of $150, even when retaining the same award type
For awards involving travel on other airlines, origin or destination changes or changes to the airline(s) in the itinerary will incur a change fee of $150, even when retaining the same award type
For AAnytime awards, origin or destination change fees are waived only when retaining the same award type
The change fee will be waived for Executive Platinum members using miles from their account
Reinstating flight awards
You can request to have your AAdvantage mileage reinstated for a wholly unused AAdvantage award ticket and if the ticket has not expired
The reinstatement charge is $150 per account for the first award ticket. Additional award tickets reinstated to the same account at the same time will have a $25 charge per ticket
This fee will be waived for Executive Platinum members using miles from their account