score:6
As you already stated, Judas (Strong's g2455) is simply a variation of the name Judah. Iscariot (Strong's g2469) translates to "man of Kerioth." Kerioth is one of the cities listed in Joshua chapter 15 as the allotment of the Promised Land for the tribe of Judah. So there doesn't seem to be a literal meaning behind the name, other than likely belonging to the tribe of Judah.
As for a non-literal significance, there is certainly a parallelism between Israel (and the kings of Judah in particular) rebelling and Judas-Iscariot betraying Jesus. Whether or not this parallelism has a further significance, I can't say.