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Regarding right livelihood- taking care of the sick is one of the few areas of social responsibility that are regularly mentioned in the oldest Buddhist texts. By this, I mean, they hadn't started thinking about literacy, pollution, and other modern progressive issues. I agree the modern Pharmaceutical business has some nasty parts. Essentially you have to trust the that the doctors will give the right medicine when the time comes and leave the ineffective medicine on the shelf.
Regarding "absence while in search of enlightenment"-- There are many versions, sects of Buddhism that do not make up a rule that says you have to be monk to be come Enlightened, and they are many version, sects of Buddhist that doesn't prohibit having a family if one is a monk. Nyingma pa, all Japanese sects, some Korean Sects, probably most American sects allow the ordained to be married.
The path of the serious UpΔsaka (lay follower) is more than the 5 precepts. Depending on the tradition, lay followers take the 8 precepts, the UpΔsaka precepts or the Bodhisattva Precepts, all of which are compatible with a lay life, i.e. holding a job and taking care of a family.
Finally, if you are serious about a career change, consider doing it in a way that allows you to continue to support your family. The historical Buddha after going forth eventually came back home after he had a successful sangha and a model for how to live without starving and his wife & child ordained. This was in part lucky circumstances-- nowadays, to make a living in Buddhism, you write books, conduct retreats and so on.